Effects of Economic Freedom on Subjective Well-Being

Are people more likely to be satisfied with their lives if they had freedom from regulations, if they had the ability to trade freely internationally? In light of the demographic aging phenomenon we are facing, the present study analyzes the relationship between economic freedom and life satisfaction among European older adults. In order to do so, we are using data from the European Health, Ageing, and Retirement Survey and Economic Freedom of the World. By using the ordered logit regression method, we estimated different models to identify how sub-indicators of economic freedom affect the subjective well-being. According to the findings, the quality of the institutions that define the legal system and establish rules for the protection of private property and sound monetary policy have a positive effect on subjective well-being. On the other hand, openness to international trade has a negative effect and government and regulation doesn’t show any significance.

TOR - Didactic pluggable transport

Considering that access to information is one of the most important aspects of modern society, the actions of certain governments or internet providers to control or, even worse, deny access for their citizens/users to selected data sources has lead to the implementation of new communication protocols. TOR is such a protocol, in which the path between the original source and destination is randomly generated using a network of globally connected routers and, by doing so, the client is not identified as actually accessing the resource. However, if the ISP knows that the first hop is part of TOR or if it can identify the contents of the exchanged packages as being TOR packages, by using advanced detection algorithms, it can still perform it’s denial policies. These types of detection are circumvented by the usage of bridges (TOR routers which aren’t publicly known) and pluggable transports (content changing protocols, in order to pass through as innocent-looking traffic). The development of a didactic pluggable transport in a simulated TOR network is the main purpose of this paper, in order to investigate the current state of the art of TOR development and analysis

Plasma hsa-mir-19b is a potential LevoDopa therapy marker

Parkinson's disease (PD) is the second most common neurodegenerative disorder among the elderly, the diagnostic and prognostic of which is based mostly on clinical signs. LevoDopa replacement is the gold standard therapy for PD, as it ameliorates the motor symptoms. However, it does not affect the progression of the disease and its long-term use triggers severe complications. There are no bona fide biomarkers for monitoring the patients' response to LevoDopa and predicting the efficacy of levodopa treatment. Here, we have combined qPCR microRNA array screening with analysis of validated miRs in naïve versus Levodopa-treated PD patients. We have identified plasma miR-19b as a possible biomarker for LevoDopa therapy and validated this result in human differentiated dopaminergic neurons exposed to LevoDopa. In silico analysis suggests that the LevoDopa-induced miR-19b regulates ubiquitin-mediated proteolysis

Ischemic Stroke in Young Adults: Practical Diagnosis Guide

With its increasing incidence in younger population and as a leading cause of disability, ischemic stroke represents a real public health problem. This chapter aims to evaluate the most common risk factors and causes for ischemic stroke in the young. Though some are identical to those found in older patients, most of them are specific to this population segment. Furthermore, another objective is to provide some guidance in approaching the case based on some important clinical clues. Due to the lack of universal management guidelines, it is up to the physician to judge the particularities of each case and to carry out the variety of investigations necessary for determining the cause

Cross-European initial survey on the use of mathematical models in food industry

Mathematical modelling plays an important role in food engineering having various mathematical models tailored for different food topics. However, mathematical models are followed by limited information on their application in food companies. This paper aims to discuss the extent and the conditions surrounding the usage of mathematical models in the context of European food and drinks industry. It investigates the knowledge, nature and current use of modelling approaches in relation to the industry main characteristics. A total of 203 food companies from 12 European countries were included in this research. Results reveal that the country where the company operates, and size of the company, are more important predictors on the usage of mathematical models followed by the type of food sector. The more developed countries are positioned at the higher level of knowledge and use of available models. Similar pattern was observed at the micro level showing that small or medium sized companies exhibit lack of knowledge, resources and limiting usage of models

CHARACTERISTICS OF CORPORATE SOCIAL RESPONSIBILITY IN THE WATER PUBLIC SECTOR IN ROMANIA

Services of water supply and sanitation in Romania has undergone major transformations in recent years, both from the technical point of view, but also from the organizational point of view. All these changes have had and have effects on the communities, positive and negative (generated from construction sites). This paper highlights the particularities of Social Responsibility Campaigns carried out by the public operators of water services from Romania in this transition to comply with the rules imposed by the European Union, with the identification of the benefits generated by these campaigns, both for operators and for the community. The the ultimate goal is to justify the necessity of implementing corporate social responsibility strategies in a transparent and the equitable manner in the area concerned

ANALYSIS OF THE STRUCTURAL FUNDS IMPACT ON ECONOMIC DEVELOPMENT IN ROMANIA

The present research objective is to analyze the impact of structural funds available in Romania during 2007 - 2013, especially for economic development of the Romania’s Western Region. The impact analysis will focus on the analysis of evolution of some socio-economic indicators such as absorption rate of structural funds, Gross Domestic Product per capita (GDP), employment rate, unemployment, job vacancies, and the average net salary. The working hypothesis is a high absorption rate of the structural funds can positively influences the economic development of the Romania and especially of the Western Region, which is subject of the case study in this paper

Mineralogical and Geochemical Implications of Weathering Processes Responsible for Soil Generation in Mănăila Alpine Area (Tulgheş 3 Unit—Eastern Carpathians)

In the Mănăila alpine area, the soil layer developed in situ on top of the sericite-schists, which belong to the Tulghes 3 metamorphic unit. The aim of the present work was to determine the degree of soil formation using both mineralogical and geochemical exploration methods. XRD, FTIR and SEM-EDS results showed that the soil constituents were dioctahedral 2:1 minerals, quartz, chlorite, Na-feldspar, rutire and ilmenite. Mainly illite and secondarily mixed-layer minerals were considered to be the most likely minerals resulting from the transformation of sericite and chlorite under acidic alpine conditions. Geochemical modeling inferred the dominance of illite and the presence of smectite as a chlorite alteration product. The weathering indices supported the moderate stage of the soil development agreeing with mineralogical observations. Because of the abundance of sericite and quartz in the parent material, the soil formation was retarded, and its present composition is still related to the bedrocks

Risk of Salinization in the Agricultural Soils of Semi-Arid Regions: A Case Study from Moldavian Plain (NE Romania)

In the present study, the salinization trends of different soil types from a small hydrographic basin situated in NE Romania (Roșior basin) are investigated. The climatic conditions are favorable for long dry summers and intensive evaporation. The soils are developed on immature evolved clay sediments, as revealed by geochemical analysis. The salinity varies among soil types, attaining maximum values for Solonetz with total dissolved salts (TDS) between 1165.75 to 1881.25 mg/L. The aqueous solutions are represented by natural water and soil solution. The hydrogeochemical facies of the natural waters change from HCO3−—Mg2+ in the upper basin to SO42−—Na+ in the middle or lower basin. The soil solution is moderately or strongly salinized and shows anionic variations from HCO3− to SO42− in the studied profiles, whereas Na+ is always the main cation. The concentrations of Na+ and SO42− evolve simultaneously. Raman spectroscopic exploration of the white efflorescences, which occur on topsoil, reveals the presence of thenardite as the dominant phase. The composition of soil solution results from both the ionic exchange and evaporation processes. The nature of soil solution mineralization and summer temperatures are two main factors that interact and promote the thenardite precipitation. The soil salinization induces negative effects on crop nutrition, impacting further the crop yields. The results of this study can be extrapolated to larger areas formed on Sarmatian sedimentary deposits affected by salinization processes

Chronotherapy Advances in the Management of Chronic Neurological and Cardiovascular Diseases: Complex Interactions of Circadian Rhythm Environmental Inputs, Nutrition and Drug Administration and Their Impact on Human Health

New scientific evidence raises awareness concerning the human-specific interplay among primary environmental conditions, such as the light–dark cycle, activity–rest alternation, nutritional patterns, and their reflection on the physiological and pathological characteristics that are displayed uniquely by every individual. One of the critical aspects in the clinic is to understand the role of circadian rhythms as remarkable modulators of the biological effects of drugs and to aim for an optimal overlapping of the time of administration of medicines with the physiologic release of certain hormones, the time-dependent expression of genes, or the key-regulatory protein synthesis, which are all circadian-driven processes. The pharmacokinetics and pharmacodynamics profiles, as well as the possible drug interactions of neurotropic and cardiovascular agents, are intensely subjected to endogenous circadian rhythms, being essential to identify as much as possible the patients’ multiple risk factors, from age and gender to lifestyle elements imprinted by dietary features, sleep patterns, psychological stress, all the way to various other associated pathological conditions and their own genetic and epigenetic background. This review chapter will highlight the involvement of biological rhythms in physiologic processes and their impact on various pathological mechanisms, and will focus on the nutritional impact on the circadian homeostasis of the organism and neurologic and cardiovascular chronotherapy